Entity Central Index Key
Held to maturity and available for sale securities accumulated unrecognized holding loss.
Held to maturity and available for sale securities accumulated unrecognized holding gain.
Available for sale securities debt maturities more than one year amortized cost.
Cover [Abstract]
Document Information [Table]
Document Information [Table]
Class of Stock
Statement Class Of Stock [Axis]
Class of Stock
Class Of Stock [Domain]
Voting common stocks.
Voting Common Stock [Member]
Voting Common Stocks [Member]
Non-voting common stocks.
Non-voting Common Stock [Member]
Non Voting Common Stocks [Member]
Document Information [Line Items]
Document Information [Line Items]
Document Type
Document Type
Amendment Flag
Amendment Flag
Document Period End Date
Document Period End Date
Document Fiscal Year Focus
Document Fiscal Year Focus
Document Fiscal Period Focus
Document Fiscal Period Focus
Entity Registrant Name
Entity Registrant Name
Entity Central Index Key
Entity Current Reporting Status
Entity Current Reporting Status
Entity Interactive Data Current
Entity Interactive Data Current
Current Fiscal Year End Date
Current Fiscal Year End Date
Entity Filer Category
Entity Filer Category
Entity Common Stock, Shares Outstanding
Entity Common Stock Shares Outstanding
Entity Shell Company
Entity Shell Company
Entity Small Business
Entity Small Business
Entity Emerging Growth Company
Entity Emerging Growth Company
Entity Ex Transition Period
Entity Ex Transition Period
Title of 12(b) Security
Security12b Title
Trading Symbol
Trading Symbol
Security Exchange Name
Security Exchange Name
Entity File Number
Entity File Number
Entity Incorporation, State or Country Code
Entity Incorporation State Country Code
Entity Tax Identification Number
Entity Tax Identification Number
Entity Address, Address Line One
Entity Address Address Line1
Entity Address, Address Line Two
Entity Address Address Line2
Entity Address, City or Town
Entity Address City Or Town
Entity Address, State or Province
Entity Address State Or Province
Entity Address, Postal Zip Code
Entity Address Postal Zip Code
City Area Code
City Area Code
Local Phone Number
Local Phone Number
Document Quarterly Report
Document Quarterly Report
Document Transition Report
Document Transition Report
Deferred revenue from collaborations current.
Deferred revenue from collaborations noncurrent.
Statement Of Financial Position [Abstract]
ASSETS
Assets [Abstract]
Current assets:
Assets Current [Abstract]
Cash and cash equivalents
Cash And Cash Equivalents At Carrying Value
Restricted cash
Restricted Cash Current
Short-term investments
Short Term Investments
Other current assets
Other Assets Current
Total current assets
Assets Current
Operating lease right-of-use assets
Operating Lease Right Of Use Asset
Property and equipment, net
Property Plant And Equipment Net
Long-term investments
Long Term Investments
Other assets
Other Assets Noncurrent
Total assets
Assets
LIABILITIES, PREFERRED STOCK, AND STOCKHOLDERS EQUITY
Liabilities And Stockholders Equity [Abstract]
Current liabilities:
Liabilities Current [Abstract]
Accounts payable
Accounts Payable Current
Accrued liabilities
Accrued Liabilities Current
Operating lease liabilities, current
Operating Lease Liability Current
Finance lease liabilities, current
Finance Lease Liability Current
Deferred revenue from collaborations, current
Deferred Revenue From Collaborations Current
Total current liabilities
Liabilities Current
Operating lease liabilities, net of current portion
Operating Lease Liability Noncurrent
Finance lease liabilities, net of current portion
Finance Lease Liability Noncurrent
Other liabilities
Other Liabilities Noncurrent
Deferred revenue from collaborations, net of current portion
Deferred Revenue From Collaborations Non Current
Total liabilities
Liabilities
Commitments and contingencies (Note 12)
Commitments And Contingencies
Stockholders’ equity:
Stockholders Equity [Abstract]
Preferred Stock, $0.0001 par value; 10,000,000 shares authorized as of September 30, 2021 (unaudited) and December 31, 2020, respectively; no shares issued and outstanding as of September 30, 2021 (unaudited) and December 31, 2020
Preferred Stock Value
Common stock, $0.0001 par value; 320,000,000 shares authorized as of September 30, 2021 (unaudited) and December 31, 2020, respectively; 42,611,847 and 38,120,606 shares issued and outstanding as of September 30, 2021 (unaudited) and December 31, 2020
Common Stock Value
Additional paid-in capital
Additional Paid In Capital Common Stock
Accumulated deficit
Retained Earnings Accumulated Deficit
Accumulated other comprehensive loss
Accumulated Other Comprehensive Income Loss Net Of Tax
Total stockholders’ equity
Stockholders Equity
Total liabilities and stockholders’ equity
Liabilities And Stockholders Equity
Preferred Stock, Par Value
Preferred Stock Par Or Stated Value Per Share
Preferred Stock, Shares Authorized
Preferred Stock Shares Authorized
Preferred Stock, Shares Issued
Preferred Stock Shares Issued
Preferred Stock, Shares Outstanding
Preferred Stock Shares Outstanding
Common Stock, Par Value
Common Stock Par Or Stated Value Per Share
Common Stock, Shares Authorized
Common Stock Shares Authorized
Common Stock, Shares, Issued
Common Stock Shares Issued
Common Stock, Shares, Outstanding
Common Stock Shares Outstanding
Income Statement [Abstract]
Revenue from collaborations
Revenue From Collaborative Arrangement Excluding Revenue From Contract With Customer
Operating expenses:
Operating Expenses [Abstract]
Research and development
Research And Development Expense
General and administrative
General And Administrative Expense
Total operating expenses
Operating Expenses
Loss from operations
Operating Income Loss
Interest and other income (expense), net
Other Operating Income Expense Net
Loss before income tax expense
Income Loss From Continuing Operations Before Income Taxes Minority Interest And Income Loss From Equity Method Investments
Income tax income (expense)
Income Tax Expense Benefit
Net loss
Net Income Loss
Other comprehensive income (loss):
Other Comprehensive Income Loss Net Of Tax Portion Attributable To Parent [Abstract]
Unrealized gain (loss) on available-for-sale securities
Other Comprehensive Income Loss Available For Sale Securities Adjustment Net Of Tax
Unrealized gain (loss) on pension plans
Other Comprehensive Income Defined Benefit Plans Adjustment Net Of Tax Portion Attributable To Parent
Other comprehensive income (loss)
Other Comprehensive Income Loss Net Of Tax Portion Attributable To Parent
Comprehensive loss
Comprehensive Income Net Of Tax
Net loss per share, basic and diluted
Earnings Per Share Basic And Diluted
Weighted average shares of common stock, basic and diluted
Weighted Average Number Of Share Outstanding Basic And Diluted
Vesting of early excercised common stock options, value.
Issuance of redeemable convertible stock on exercise of warrants, value.
Vesting of early exercised common stock options from existing exercises value.
Statement Of Stockholders Equity [Abstract]
Statement [Table]
Statement [Table]
Equity Components
Statement Equity Components [Axis]
Equity Component
Equity Component [Domain]
Common Stock
Common Stock [Member]
Additional Paid-in Capital
Additional Paid In Capital [Member]
Accumulated Deficit
Retained Earnings [Member]
Accumulated Other Comprehensive Income (Loss)
Accumulated Other Comprehensive Income [Member]
Series A
Series A Preferred Stock [Member]
Series B-1
Series B Preferred Stock [Member]
Statement [Line Items]
Statement [Line Items]
Beginning balance
Beginning balance, Shares
Temporary Equity Shares Outstanding
Beginning balance
Temporary Equity Carrying Amount Attributable To Parent
Beginning balance, Shares
Shares Outstanding
Issuance of common stock upon exercise of stock options
Stock Issued During Period Value Stock Options Exercised
Issuance of common stock upon exercise of stock options, shares
Stock Issued During Period Shares Stock Options Exercised
Issuance of Series A stock upon exercise of Series A warrants
Issuance Of Redeemable Convertible Stock On Exercise Of Warrants Value
Issuance of redeemable convertible stock on exercise of warrants, shares.
Issuance of Series A stock upon exercise of Series A warrants, shares
Issuance Of Redeemable Convertible Stock On Exercise Of Warrants Shares
Issuance of common stock in connection with Follow-on Offering, net of offering costs
Stock Issued During Period Value New Issues
Issuance of common stock in connection with Follow-on Offering, net of offering costs, shares
Stock Issued During Period Shares New Issues
Costs related to the Follow-on Offering
Adjustments To Additional Paid In Capital Stock Issued Ownshare Lending Arrangement Issuance Costs
Stock-based compensation
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
Vesting of early exercised common stock options
Vesting Of Early Excercised Common Stock Options Value
Vesting of early exercised options from existing exercises
Vesting Of Early Exercised Common Stock Options From Existing Exercises Value
Other comprehensive income (loss)
Net loss
Ending balance
Ending balance, Shares
Ending balance
Ending balance, Shares
Change in fair value of redeemable convertible preferred stock liability.
Increase decrease in operating lease liabilities.
Payments on deferred offering costs.
Statement Of Cash Flows [Abstract]
Sale of Stock
Subsidiary Sale Of Stock [Axis]
Sale of Stock
Sale Of Stock Name Of Transaction [Domain]
Follow-on offering member.
Follow-on Offering [Member]
Follow On Offering [Member]
Cash flows from operating activities:
Net Cash Provided By Used In Operating Activities [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract]
Accretion of discount on investments
Accretion Amortization Of Discounts And Premiums Investments
Amortization of right of use assets
Operating Lease Right Of Use Asset Amortization Expense
Depreciation expense
Depreciation
Stock-based compensation including ESPP
Share Based Compensation
Change in fair value of derivative liability
Derivative Gain Loss On Derivative Net
Change in fair value of redeemable convertible preferred stock liabilities
Change In Fair Value Of Redeemable Convertible Preferred Stock Liability
Changes in operating assets and liabilities:
Increase Decrease In Operating Capital [Abstract]
Other assets
Increase Decrease In Other Current Assets
Accounts payable
Increase Decrease In Accounts Payable
Accrued liabilities
Increase Decrease In Accrued Liabilities
Operating lease liabilities
Increase Decrease In Operating Lease Liabilities
Other liabilities
Increase Decrease In Other Operating Liabilities
Deferred revenue from collaborations
Increase Decrease In Deferred Revenue
Net cash and cash equivalents used in operating activities
Net Cash Provided By Used In Operating Activities
Cash flows from investing activities:
Net Cash Provided By Used In Investing Activities [Abstract]
Activities in available-for-sale investments:
Available For Sale Securities [Abstract]
Maturities of investments
Proceeds From Sale Of Available For Sale Securities Debt
Purchase of short-term investments
Payments To Acquire Short Term Investments
Purchase of long-term investments
Payments To Acquire Longterm Investments
Activities in held-to-maturity investments:
Held To Maturity Securities Classified [Abstract]
Maturities of investments
Proceeds From Sale Of Held To Maturity Securities
Purchases of property and equipment
Payments To Acquire Property Plant And Equipment
Net cash and cash equivalents provided by investing activities
Net Cash Provided By Used In Investing Activities
Cash flows from financing activities:
Net Cash Provided By Used In Financing Activities [Abstract]
Proceeds from issuance of common stock in connection with Follow-on Offering, net of costs
Proceeds From Issuance Of Common Stock
Proceeds from exercise of warrants for series A convertible preferred stock
Proceeds From Warrant Exercises
Payment of Series B-1 redeemable convertible preferred stock issuance cost
Payment Of Financing And Stock Issuance Costs
Payments of deferred offering costs
Payments On Deferred Offering Costs
Payments on finance lease
Finance Lease Principal Payments
Proceeds from the exercise of common stock option
Proceeds From Stock Options Exercised
Net cash and cash equivalents provided by (used in) financing activities
Net Cash Provided By Used In Financing Activities
Net increase (decrease) in cash, cash equivalents, and restricted cash
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Excluding Exchange Rate Effect
Cash, cash equivalents, and restricted cash, beginning of period
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
Cash, cash equivalents, and restricted cash, end of period
Leasehold improvement directly paid by the landlord.
Market to market adjustments for available for sale investments.
Vesting of early exercised options value.
Receivable from the exercise of common stock options.
Change in pension obligation.
Deferred offering costs in accounts payable and accrued liabilities
Reconciliation to the amounts on the condensed consolidated balance sheet [Abstract].
Reconciliation to amounts on the consolidated balance sheet:
Reconciliation To The Amounts On The Condensed Consolidated Balance Sheet [Abstract]
Restricted cash
Restricted Cash
Supplemental disclosures of cash flow information:
Supplemental Cash Flow Elements [Abstract]
Interest paid
Interest Paid
Supplemental disclosures of noncash financing and investing activities:
Cash Flow Noncash Investing And Financing Activities Disclosure [Abstract]
Leasehold improvement directly paid by landlord
Leasehold Improvement Directly Paid By The Landlord
Mark to market adjustment for available-for-sale investments
Market To Market Adjustments For Available For Sale Investments
Acquisition of right of use asset through operating lease obligation
Right Of Use Asset Obtained In Exchange For Operating Lease Liability
Change in fair value of derivative liability upon exercise of warrants
Fair Value Adjustment Of Warrants
Vesting of early exercised options
Vesting Of Early Exercised Options Value
Receivable from exercise of common stock options
Receivable From The Exercise Of Common Stock Options
Change in pension obligation
Change In Pension Obligation
Deferred offering costs in AP and accrued liabilities
Deferred Offering Costs In Accounts Payable And Accrued Liabilities
Organization Consolidation And Presentation Of Financial Statements [Abstract]
Organization
Nature Of Operations
Accounting Policies [Abstract]
Summary of significant accounting policies
Significant Accounting Policies [Text Block]
Property Plant And Equipment [Abstract]
Property and equipment
Property Plant And Equipment Disclosure [Text Block]
Debt Securities Available For Sale And Held To Maturity [Abstract]
Investments
Investments In Debt And Marketable Equity Securities And Certain Trading Assets Disclosure [Text Block]
Payables And Accruals [Abstract]
Accrued liabilities
Accounts Payable And Accrued Liabilities Disclosure [Text Block]
Leases [Abstract]
Leases
Leases Of Lessee Disclosure [Text Block]
Derivative liabilities and redeemable convertible preferred stock liability.
Derivative Liabilities And Redeemable Convertible Preferred Stock Liability [Abstract]
Derivative Liabilities And Redeemable Convertible Preferred Stock Liability [Abstract]
Derivative liabilities and convertible preferred stock liability
Derivative Liabilities And Redeemable Convertible Preferred Stock Liability [Text Block]
Equity [Abstract]
Capital stock
Stockholders Equity Note Disclosure [Text Block]
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]
Stock-based compensation
Disclosure Of Compensation Related Costs Share Based Payments [Text Block]
Fair Value Disclosures [Abstract]
Fair value
Fair Value Disclosures [Text Block]
License and collaboration agreements text block.
License and collaboration agreements [Abstract]
License And Collaboration Agreements [Abstract]
License and collaboration agreements
License And Collaboration Agreements [Text Block]
Commitments And Contingencies Disclosure [Abstract]
Commitments and contingencies
Commitments And Contingencies Disclosure [Text Block]
Income Tax Disclosure [Abstract]
Income taxes
Income Tax Disclosure [Text Block]
Earnings Per Share [Abstract]
Net loss per share
Earnings Per Share [Text Block]
Subsequent Events [Abstract]
Subsequent events
Subsequent Events [Text Block]
Risk and uncertainity [Policy text block].
Risks and uncertainties
Risk And Uncertainity Policy [Text Block]
Basis of presentation
Basis Of Accounting Policy Policy [Text Block]
Principles of consolidation
Consolidation Policy [Text Block]
Use of estimates
Use Of Estimates
Unaudited interim financial information.
Unaudited interim financial information
Unaudited Interim Financial Information Policy [Text Block]
Deferred offering costs [Policy text block].
Deferred offering costs
Deferred Offering Costs Policy [Text Block]
Foreign currency
Foreign Currency Transactions And Translations Policy [Text Block]
Segment information
Segment Reporting Policy Policy [Text Block]
Cash equivalents
Cash And Cash Equivalents Policy [Text Block]
Restricted cash
Cash And Cash Equivalents Restricted Cash And Cash Equivalents Policy
Leases
Lessee Leases Policy [Text Block]
Property and equipment
Property Plant And Equipment Policy [Text Block]
Impairment of long-lived assets
Impairment Or Disposal Of Long Lived Assets Including Intangible Assets Policy Policy [Text Block]
Investments
Marketable Securities Policy
Research and development expenses
Research And Development Expense Policy
Collaborative arrangements
Collaborative Arrangement Accounting Policy
Fair value measurements
Fair Value Measurement Policy Policy [Text Block]
Stock-based compensation
Share Based Compensation Option And Incentive Plans Policy
Net loss per share
Earnings Per Share Policy [Text Block]
Recently issued accounting pronouncements not yet adopted [Policy text block].
Recently issued accounting standards
Recently Issued Accounting Pronouncements Not Yet Adopted Policy [Text Block]
Schedule of estimated useful life of asset.
Summary of Estimated Useful Life of Asset
Schedule Of Estimated Useful Life Of Asset Table [Text Block]
Summary of Property and Equipment
Property Plant And Equipment [Text Block]
Summary of available for sale and held to maturity securities amortized cost gross unrealized gains losses and fair value.
Summary of Available For Sale and Held to Maturity Securities Amortized Cost Gross Unrealized Gains Losses and Fair Value
Summary Of Available For Sale And Held To Maturity Securities Amortized Cost Gross Unrealized Gains Losses And Fair Value Table [Text Block]
Debt securities available for sale maturity.
Summary of Debt Securities Available for Sale Maturity
Debt Securities Available For Sale Maturity Table [Text Block]
Summary of Accrued Liabilities
Schedule Of Accrued Liabilities Table [Text Block]
Summary of Maturities of Lease Liabilities
Lessee Operating Lease Liability Maturity Table [Text Block]
Summary of Components of lease Expense
Lease Cost Table [Text Block]
Schedule of additional information related to the leases table text block
Summary of Additional Information Related to the Leases
Schedule Of Additional Information Related To The Leases Table [Text Block]
Award Type
Award Type [Axis]
Award Type
Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain]
Restricted Stock [Member]
Restricted Stock [Member]
Summary of Stock Options
Disclosure Of Share Based Compensation Arrangements By Share Based Payment Award [Text Block]
Summary of Stock Based Compensation Expense Was Allocated
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Text Block]
Summary of fair value of the financial instruments that are measured at fair value on a recurring basis
Fair Value Assets Measured On Recurring Basis [Text Block]
Schedule of Earnings Per Share, Basic and Diluted
Schedule Of Earnings Per Share Basic And Diluted Table [Text Block]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Text Block]
Nature of operations [Line items].
Nature of operations [Table].
Nature Of Operations [Table]
Nature Of Operations [Table]
IPO
I P O [Member]
Over-Allotment Option [Member]
Over Allotment Option [Member]
Stock Conversion Description
Conversion Of Stock By Unique Description [Axis]
Conversion of Stock, Name
Conversion Of Stock Name [Domain]
Conversion of stock voting shares.
Conversion Of Stock Voting Shares [Member]
Conversion Of Stock Voting Shares [Member]
Conversion of stock non voting shares.
Conversion Of Stock Non Voting Shares [Member]
Conversion Of Stock Non Voting Shares [Member]
Nature Of Operations [Line Items]
Nature Of Operations [Line Items]
Reverse stock split
Stockholders Equity Reverse Stock Split
Underwriting discounts and commissions.
Offer expenses.
Stock issued during the period new issues shares
Sale of stock issue price per share
Sale Of Stock Price Per Share
Sale of stock net consideration received on the transaction
Sale Of Stock Consideration Received On Transaction
Underwriting discounts and commissions
Underwriting Discounts And Commissions
Offer expenses
Offer Expenses
Temporary equity shares converted into permanent equity
Conversion Of Stock Shares Converted1
Accumulated deficit
Unrestricted cash, Cash equivalent and investment
Cash Cash Equivalents And Short Term Investments
Financing Sources [Table]
Financing Sources [Table]
Balance Sheet Location
Balance Sheet Location [Axis]
Balance Sheet Location
Balance Sheet Location [Domain]
Other Noncurrent Assets [Member]
Other Noncurrent Assets [Member]
Product and Service
Product Or Service [Axis]
Product and Service
Products And Services [Domain]
Product [Member]
Product [Member]
Geographical
Statement Geographical [Axis]
Geographical
Segment Geographical [Domain]
US
U S
Belgium
B E
Financing Sources [Line Items]
Financing Sources [Line Items]
Stock issued during the period new issues shares
Deferred offering costs
Deferred Offering Costs
Re-measurement gain (loss)
Foreign Currency Transaction Gain Loss Before Tax
Number of reportable segments
Number Of Reportable Segments
Cash equivalent qualification, description
Additional Cash And Cash Equivalent Related Text
Schedule Of Property Plant And Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Long-Lived Tangible Asset
Property Plant And Equipment By Type [Axis]
Long-Lived Tangible Asset
Property Plant And Equipment Type [Domain]
Lab equipment.
Lab Equipment [Member]
Lab Equipment [Member]
Computer Equipment [Member]
Computer Equipment [Member]
Furniture and Office Equipment [Member]
Furniture And Fixtures [Member]
Vehicles [Member]
Vehicles [Member]
Leasehold Improvements [Member]
Leasehold Improvements [Member]
Statistical Measurement
Range [Axis]
Statistical Measurement
Range [Member]
Minimum [Member]
Minimum [Member]
Maximum [Member]
Maximum [Member]
Property Plant And Equipment [Line Items]
Property Plant And Equipment [Line Items]
Estimated useful life of asset
Property Plant And Equipment Useful Life
Estimated useful life of asset
Property Plant And Equipment Estimated Useful Lives
Impairment of long lived assets
Impairment Of Long Lived Assets Held For Use
Other than temporary impairment losses, investments
Impairment Of Investments
Expenses on milestone payments.
Royalties due
Accrued Royalties Current And Noncurrent
Expenses on milestone payments
Expenses On Milestone Payments
Payments for royalties
Payments For Royalties
Dividends, common stock, cash
Dividends Common Stock Cash
Expected dividend yield
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
Leasehold improvements [Member]
Lab equipment [Member]
Equipment [Member]
Computer equipment [Member]
Furniture and office equipment [Member]
Asset under construction [Member]
Asset Under Construction [Member]
Total, at cost
Property Plant And Equipment Gross
Accumulated depreciation
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
Total, net
Held to maturity and available for sale securities amortized cost basis.
Schedule of available for sale and held to maturity securities amortised cost gross unrealised gains losses and fair value [Line items].
Schedule of available for sale and held to maturity securities amortised cost gross unrealised gains losses and fair value [Table].
Schedule Of Available For Sale And Held To Maturity Securities Amortised Cost Gross Unrealised Gains Losses And Fair Value [Table]
Schedule Of Available For Sale And Held To Maturity Securities Amortised Cost Gross Unrealised Gains Losses And Fair Value [Table]
Cash and Cash Equivalents
Cash And Cash Equivalents [Axis]
Cash and Cash Equivalents
Restricted Cash And Cash Equivalents Cash And Cash Equivalents [Member]
Certificates of deposit [Member]
Certificates Of Deposit [Member]
U.S. Treasury bonds [Member]
U S Treasury Securities [Member]
Schedule Of Available For Sale And Held To Maturity Securities Amortised Cost Gross Unrealised Gains Losses And Fair Value [Line Items]
Schedule Of Available For Sale And Held To Maturity Securities Amortised Cost Gross Unrealised Gains Losses And Fair Value [Line Items]
Available-for-sale securities, Amortized Cost
Available For Sale Debt Securities Amortized Cost Basis
Available-for-sale securities, Gross Unrealized Gain
Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax
Available-for-sale securities, Gross Unrealized Loss
Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax
Available-for-sale securities, Estimated Fair Value
Available For Sale Securities Debt Securities
Total Held-to-maturity securities and Available for-sale securities Amortized Cost
Held To Maturity And Available For Sale Securities Amortized Cost Basis
Total Held-to-maturity securities and Available for-sale securities Gross Unrealized Loss
Held To Maturity And Available For Sale Securities Accumulated Unrecognized Holding Loss
Total Held-to-maturity securities and Available for-sale securities Estimated Fair Value
Available For Sale Securities And Held To Maturity Securities
Held-to-maturity securities, Amortized Cost
Held To Maturity Securities
Held-to-maturity securities, Gross Unrealized Gain
Held To Maturity Securities Accumulated Unrecognized Holding Gain
Held-to-maturity securities, Gross Unrealized Loss
Held To Maturity Securities Accumulated Unrecognized Holding Loss
Held-to-maturity securities, Estimated Fair Value
Held To Maturity Securities Fair Value
Total Held-to-maturity securities and Available for-sale securities Gross Unrealized Gain
Held To Maturity And Available For Sale Securities Accumulated Unrecognized Holding Gain
Available for sale securities debt maturities more than one year fair value.
Available For Sale Securities Debt Maturities [Abstract]
Available-for-Sale, Amortized Cost, One year or less
Available For Sale Securities Debt Maturities Within One Year Amortized Cost
Available-for-Sale, Amortized Cost, More than one year
Available For Sale Securities Debt Maturities More Than One Year Amortized Cost
Available-for-Sale, Estimated Fair Value, One year or less
Available For Sale Securities Debt Maturities Within One Year Fair Value
Available-for-Sale, Estimated Fair Value, More than one year
Available For Sale Securities Debt Maturities More Than One Year Fair Value
Available-for-sale, Estimated Fair Value, Total investments
Investment in available for sale and held to maturity securities.
Investment in available for sale and held to maturity securities [Table].
Investment In Available For Sale And Held To Maturity Securities [Table]
Investment In Available For Sale And Held To Maturity Securities [Table]
Debt Security Category
Information By Category Of Debt Security [Axis]
Other than Temporary Impairment, Credit Losses Recognized in Earnings, Categories of Investments
Other Than Temporary Impairment Credit Losses Recognized In Earnings Categories Of Investments [Domain]
Fixed-Maturity Securities [Member]
Fixed Maturities [Member]
Investment In Available For Sale And Held To Maturity Securities [Line Items]
Investment In Available For Sale And Held To Maturity Securities [Line Items]
Interest income
Interest Income Expense Net
Accrued payables current.
Liability for early exercised stock options current.
Accrued compensation
Employee Related Liabilities Current
Accrued payables
Accrued Payables Current
Liability for early exercised stock options
Liability For Early Exercised Stock Options Current
Other
Other Accrued Liabilities Current
Total
Lessee remaining lease term of operating and finance lease.
Lessee Operating Lease Option To Extend Term.
Lessee Lease Description [Table]
Lessee Lease Description [Table]
Lessee Lease Description [Line Items]
Lessee Lease Description [Line Items]
Operating and finance lease remaining lease term
Lessee Remaining Lease Term
Operating lease option to extend
Lessee Operating Lease Option To Extend Term
Lessee operating lease liability payments due after year four.
Schedule Of Maturities Of Lease Liabilities [Abstract]
Operating Lease
Operating Lease Liabilities Payments Due [Abstract]
2021, remainder
Lessee Operating Lease Liability Payments Remainder Of Fiscal Year
2022
Lessee Operating Lease Liability Payments Due Next Twelve Months
2023
Lessee Operating Lease Liability Payments Due Year Two
2024
Lessee Operating Lease Liability Payments Due Year Three
2025
Lessee Operating Lease Liability Payments Due Year Four
Thereafter
Lessee Operating Lease Liability Payments Due After Year Four
Lessee, Operating Lease, Liability, to be Paid
Lessee Operating Lease Liability Payments Due
Less: imputed interest
Lessee Operating Lease Liability Undiscounted Excess Amount
Present value of lease liabilities
Operating Lease Liability
Less: current portion
Lease liabilities net of current portion
Finance lease liability payments due after year four.
Finance Lease
Finance Lease Liabilities Payments Due [Abstract]
2021, remainder
Finance Lease Liability Payments Remainder Of Fiscal Year
2022
Finance Lease Liability Payments Due Next Twelve Months
2023
Finance Lease Liability Payments Due Year Two
2024
Finance Lease Liability Payments Due Year Three
2025
Finance Lease Liability Payments Due Year Four
Thereafter
Finance Lease Liability Payments Due After Year Four
Finance Lease, Liability, Payment, Due
Finance Lease Liability Payments Due
Less: imputed interest
Finance Lease Liability Undiscounted Excess Amount
Present value of lease liabilities
Finance Lease Liability
Less: current portion
Lease liabilities net of current portion
Finance lease amortization of right of use assets.
Finance Lease Cost
Finance lease costs.
Lease Cost [Abstract]
Operating lease cost
Operating Lease Cost
Finance lease cost:
Finance Lease Costs [Abstract]
Amortization of right-of-use assets
Finance Lease Amortization Of Right Of Use Assets
Interest on lease liabilities
Finance Lease Interest Expense
Total finance lease cost
Finance Lease Cost
Operating lease, payments
Operating Lease Payments
Finance lease right of use assets
Finance Lease Right Of Use Asset Before Accumulated Amortization
Finance lease right of use assets accumulated amortization
Finance Lease Right Of Use Asset Accumulated Amortization
Schedule of additional information related to the leases
Schedule Of Additional Information Related To The Leases [Abstract]
Weighted-average remaining lease term (years)
Operating Lease Weighted Average Remaining Lease Term1
Weighted-average discount rate
Operating Lease Weighted Average Discount Rate Percent
Weighted-average remaining lease term (years)
Finance Lease Weighted Average Remaining Lease Term1
Weighted-average discount rate
Finance Lease Weighted Average Discount Rate Percent
Percentage of principal amount of notes covered by warrants.
Warrants and rights outstanding maturity period.
Warrants issued closing date.
Derivative liabilities and convertible preferred stock liability [line items].
Derivative Liabilities And Redeemable Convertible Preferred Stock Liability [Table]
Derivative Liabilities And Redeemable Convertible Preferred Stock Liability [Table]
Liability Class
Fair Value By Liability Class [Axis]
Fair Value by Liability Class
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation By Liability Class [Domain]
Derivative Financial Instruments, Liabilities [Member]
Derivative Financial Instruments Liabilities [Member]
Warrant [Member]
Warrant [Member]
Series B Two Preferred Stock [Member]
Series B Two Preferred Stock [Member]
Series B Two Preferred Stock [Member]
Mandatorily Redeemable Preferred Stock [Member]
Mandatorily Redeemable Preferred Stock [Member]
Derivative Liabilities And Convertible Preferred Stock Liability [Line Items]
Derivative Liabilities And Convertible Preferred Stock Liability [Line Items]
Class of warrant or right, number of securities called by warrants or rights
Class Of Warrant Or Right Number Of Securities Called By Warrants Or Rights
Percentage of principal amount of notes covered by warrants
Percentage Of Principal Amount Of Notes Covered By Warrants
Warrants issued expiry period
Warrants And Rights Outstanding Maturity Period
Warrants issued closing date
Warrants Issued Closing Date
Warrants exercise price per share
Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1
Fair value of warrants upon issuance.
Fair value of warrants upon issuance
Fair Value Of Warrants Upon Issuance
Fair value of the warrants
Derivative Liabilities
Warrants exercised.
Warrants exercised
Warrants Exercised
Changes in fair value of the warrants
Sale of Stock, Number of Shares Issued in Transaction
Sale Of Stock Number Of Shares Issued In Transaction
Redeemable convertible preferred stock liability at a fair value
Mandatorily Redeemable Preferred Stock Fair Value Disclosure
Change in fair value of liability
Servicing Liability At Fair Value Period Increase Decrease
Voting common stock.
Voting Common Stock [Member]
Voting Common Stock [Member]
Non-Voting Common Stock [Member]
Nonvoting Common Stock [Member]
Series A Preferred Stock [Member]
Series A [Member]
Series A [Member]
Series B Preferred Stock [Member]
Series B one preferred stock.
Series B One Preferred Stock [Member]
Series B One Preferred Stock [Member]
Number of shares of common stock authorized
Number of shares of preferred stock authorized
Temporary Equity Shares Authorized
Preferred stock authorized par value
Common stock voting right
Common Stock Voting Rights
Preferred Stock Conversion Split.
Stock issuance costs.
Sale of stock, consideration received on transaction
Conversion of convertible notes to redeemable convertible preferred stock
Stock Issued During Period Value Conversion Of Convertible Securities
Preferred Stock, Conversion split
Preferred Stock Conversion Split
Stock issuance costs
Stock Issuance Costs
Preferred stock issued
Temporary Equity Shares Issued
Compensation Related Costs [Abstract]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Stock Option [Member]
Employee Stock Option [Member]
Employee stock purchase plan.
Employee Stock Purchase Plan [Member]
Employee Stock Purchase Plan [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share based compensation expense
Allocated Share Based Compensation Expense
Share based compensation expense recognized tax benefit
Employee Service Share Based Compensation Tax Benefit From Compensation Expense
Share based payment unamortized share based payment expenses
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized
Share based payment expenses amortized over a weighted average period
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Number of options - Beginning balance
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
Number of options, Granted
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
Number of options, Exercised
Number of options, Cancelled
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period
Number of options - Ending balance
Number of options vested and expected to vest
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Number
Number of options vested and exercisable
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
Weighted average exercise price - Beginning balance
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
Weighted average exercise price Granted
Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
Weighted average exercise price Exercised
Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
Weighted average exercise price Cancelled
Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price
Weighted Average Exercise Price - Ending balance
Weighted average exercise price Options vested and expected to vest
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Exercise Price
Weighted average exercise price options vested and exercisable
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
Weighted- Average Remaining Contractual Term, Outstanding
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
Weighted- Average Remaining Contractual Term, Options vested and expected to vest
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Remaining Contractual Term1
Weighted- Average Remaining Contractual Term, Options vested and exercisable
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1
Aggregate Intrinsic Value - Options outstanding
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
Aggregate Intrinsic Value - Exercised
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
Aggregate Intrinsic Value - Options outstanding
Aggregate Intrinsic Value, options vested and expected to vest
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Aggregate Intrinsic Value
Aggregate Intrinsic Value, Options vested and exercisable
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Exercisable Aggregate Intrinsic Value
Share based payments weighted-average grant date fair value
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested Weighted Average Grant Date Fair Value
Number of awards - Beginning balance
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
Number of awards, granted
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period
Number of awards, vested
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period
Number of awards - Ending balance
Weighted average granted fair date value - Beginning balance
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
Weighted average granted fair date value, granted
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Weighted Average Grant Date Fair Value
Weighted average granted fair date value, vested
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Weighted Average Grant Date Fair Value
Weighted average granted fair date value - Ending balance
Share based compensation arrangement by share based payment award equity instruments other than options aggregate intrinsic value granted.
Aggregate intrinsic value - Beginning
Sharebased Compensation Arrangement By Sharebased Payment Award Equity Instruments Other Than Options Aggregate Intrinsic Value Outstanding
Aggregate intrinsic value, Granted
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Aggregate Intrinsic Value Granted
Aggregate intrinsic value, Vested
Sharebased Compensation Arrangement By Sharebased Payment Award Equity Instruments Other Than Options Aggregate Intrinsic Value Vested
Aggregate intrinsic value - Ending balance
Stock issues early period share stock options exercised.
Aggregate share repurchase price.
Common stock issued upon exercise of stock options
Stock Issues Early Period Share Stock Options Exercised
Shares of common stock held by employees subject to repurchase
Weighted Average Number Of Shares Common Stock Subject To Repurchase Or Cancellation
Share price
Aggregate Share Repurchase Price
Purchase of common stock
Stock Issued During Period Shares Employee Stock Purchase Plans
Income Statement Location
Income Statement Location [Axis]
Income Statement Location
Income Statement Location [Domain]
Research and Development [Member]
Research And Development Expense [Member]
General and Administrative [Member]
General And Administrative Expense [Member]
Allocated Share Based Compensation Expense
Disclosure - Fair value - Summary of Fair Value of the Financial Instruments that are Measured at Fair Value on a Recurring Basis (Detail) [Abstract]
Disclosure Fair Value Summary Of Fair Value Of Financial Instruments That Are Measured At Fair Value On Recurring Basis Detail [Abstract]
Fair Value Hierarchy and NAV
Fair Value By Fair Value Hierarchy Level [Axis]
Fair Value Hierarchy and NAV
Fair Value Measurements Fair Value Hierarchy [Domain]
Level 1 [Member]
Fair Value Inputs Level1 [Member]
Level 2 [Member]
Fair Value Inputs Level2 [Member]
Level 3 [Member]
Fair Value Inputs Level3 [Member]
Asset Class
Fair Value By Asset Class [Axis]
Asset Class
Fair Value Assets Measured On Recurring Basis Unobservable Input Reconciliation By Asset Class [Domain]
Assets:
Financial Instruments Financial Assets Balance Sheet Groupings [Abstract]
Cash equivalents
Cash And Cash Equivalents Fair Value Disclosure
Fair value, assets
Investments Fair Value Disclosure
Fair value, assets
Assets Fair Value Disclosure
Upfront license fees paid
Disclosure - License and collaboration agreements - Additional Information (Detail) [Abstract]
Disclosure License And Collaboration Agreements Additional Information Detail [Abstract]
Research and Development [Member]
Research and Development Arrangement, Contract to Perform for Others, Type
Research And Development Arrangement Contract To Perform For Others By Type [Axis]
Research and Development Arrangement, Contract to Perform for Others, Type
Research And Development Arrangement Contract To Perform For Others Type [Domain]
Emory license agreement.
Emory license agreement [Member]
Emory License Agreement [Member]
Related Party
Related Party Transactions By Related Party [Axis]
Related Party
Related Party [Domain]
Emory university [Member]
Emory university [Member]
Emory University [Member]
Luxna license agreement [Member]
Luxna license agreement [Member]
Luxna License Agreement [Member]
Luxna biotech Co Ltd [Member]
Luxna biotech Co Ltd [Member]
Luxna Biotech Co Ltd [Member]
Katholieke Universiteit Leuven License Agreement.
Katholieke Universiteit Leuven License Agreement [Member]
Katholieke Universiteit Leuven License Agreement [Member]
KU Leuven.
KU Leuven [Member]
K U Leuven [Member]
Katholieke Universiteit Leuven.
Katholieke Universiteit Leuven [Member]
Katholieke Universiteit Leuven [Member]
Merck license and research collaboration.
Merck License and Research Collaboration [Member]
Merck License And Research Collaboration [Member]
Merck.
Merck [Member]
Merck [Member]
Upfront license fees paid
Upfront License Fees Paid
Convertible notes issued for purchasing license
Notes Issued1
Debt instrument, conversion price
Debt Instrument Convertible Conversion Price1
Long term purchase commitment additional obligation to be paid.
Research and development arrangement contract to perform for others expiry period.
Long term purchase commitment period description.
Non-refundable payment
Long Term Purchase Commitment Amount
Long term purchase commitment additional obligation to be paid
Long Term Purchase Commitment Additional Obligation To Be Paid
Research plan funding amount
Research And Development Arrangement Contract To Perform For Others Costs Incurred Gross
Research plan expiry period
Research And Development Arrangement Contract To Perform For Others Expiry Period
Long term purchase commitment period description
Longterm Purchase Commitment Period Description
Expense related to milestone payments.
Expense or accruals recognized related to royalties.
Aggregate payments
Contractual Obligation
Expense related to milestone payments
Expense Related To Milestone Payments
Expense or accruals recognized related to royalties
Expense Or Accruals Recognized Related To Royalties
First commercial sale of a licensed product period.
Collaboration expire period
Longterm Purchase Commitment Period
First commercial sale of a licensed product period
First Commercial Sale Of A Licensed Product Period
Milestone payments and royalties receivable.
Milestone payments and royalties receivable
Milestone Payments And Royalties Receivable
Revenue recognized from collaborative arrangements
Contract With Customer Liability Revenue Recognized
Contingent liabilities
Loss Contingency Accrual At Carrying Value
Non-cancellable purchase commitments
Purchase Obligation
Earnings Per Share Basic And Diluted [Abstract]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Antidilutive Securities
Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis]
Antidilutive Securities, Name
Antidilutive Securities Name [Domain]
Convertible preferred stock [Member]
Convertible Preferred Stock [Member]
Forward contract to issue redeemable convertible preferred stock [Member]
Forward Contracts [Member]
Options to purchase common stock [Member]
Unvested restricted stock [Member]
Warrants to purchase preferred stock [Member]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Antidilutive securities excluded from computation of earnings per share, amount
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount