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Research plan expiry period Research And Development Arrangement Contract To Perform For Others Expiry Period Research and development arrangement contract to perform for others expiry period. Share-based Payment Arrangement [Abstract] Share-Based Payment Arrangement [Abstract] Disposal Group Classification [Domain] Dividends, common stock, cash Dividends, Common Stock, Cash Excercise price of stock per share Common Stock Exercise Price Per Share Common stock in exercise price per share. Accounts Payable, Current, Total Accounts payable Accounts Payable, Current ROU asset Increase decrease in right of use assets. 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Common stock issued upon exercise of stock options Stock Issues Early Period Share Stock Options Exercised Stock issues early period share stock options exercised. Subsequent Event Type [Domain] Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum Risk-free interest rate, minimum Income Statement Location Income Statement Location [Axis] Accelerated Share Repurchases, Date [Domain] Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum Risk-free interest rate, maximum Top Hat Plan [Member] Top Hat Plan [Member] Top Hat Plan. Dividend yield Expected dividend yield Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Common Warrants Common Warrants [Member] Common warrants, Deferred Tax Assets, Deferred Income Deferred revenue 2028 Lessee, Operating Lease, Liability, to be Paid, Year Five Non-refundable payment Long-Term Purchase Commitment, Amount Common warrants liability Stockholders' Equity, Policy [Policy Text Block] Level 2 [Member] Fair Value, Inputs, Level 2 [Member] Katholieke Universiteit Leuven [Member] Katholieke Universiteit Leuven [Member] Katholieke Universiteit Leuven. Equipment acquired through finance lease Right-of-Use Asset Obtained in Exchange for Finance Lease Liability Title of 12(b) Security Title of 12(b) Security Luxna biotech Co Ltd [Member] Luxna Biotech Co Ltd [Member] Luxna biotech Co Ltd [Member] Warrant liability Warrant Liability Noncurrent Warrant liability noncurrent. Financial Instruments Financial Assets And Liabilities Balance Sheet Groupings [Abstract] Financial Instruments Financial Assets And Liabilities Balance Sheet Groupings [Abstract] Government contract, duration Government Assistance, Transaction Duration Foreign tax Antisense Oligonucleotide Antisense Oligonucleotide [Member] Antisense Oligonucleotide. Summary of Available For Sale and Held to Maturity Securities Amortized Cost Gross Unrealized Gains Losses and Fair Value Summary Of Available For Sale And Held To Maturity Securities Amortized Cost Gross Unrealized Gains Losses And Fair Value Table [Text Block] Summary of available for sale and held to maturity securities amortized cost gross unrealized gains losses and fair value. Combined price per, pre-funded warrant and common warrant Combined Purchase Price Per Pre Funded Warrant And Accompanying Warrant Combined purchase price of one pre-funded warrant and accompanying warrant. Cash flows from investing activities: Net Cash Provided by (Used in) Investing Activities [Abstract] Exercisable at December 31, 2023 Common Warrant Shares Exercisable Common warrant shares exercisable. State [Member] State and Local Jurisdiction [Member] Benefit plans Postemployment Benefit Plans, Policy [Policy Text Block] Segment information Segment Reporting, Policy [Policy Text Block] Summary of Maturities of Lease Liabilities Schedule Of Maturities Of Lease Liabilities Table [Text Block] Schedule of maturities of lease liabilities table text block Long-Lived Tangible Asset Long-Lived Tangible Asset [Domain] Subsequent Event [Table] Restricted cash Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block] Purchase Obligation, Total Purchase Obligation Non-cancellable purchase commitments Ending balance, shares Beginning balance, shares Common Warrant Shares Outstanding Common warrant shares outstanding. Incremental compensation cost associated with the replacement options Incremental Compensation Cost Associated With The Replacement Options Incremental compensation cost associated with the replacement options. Cap period Cap Period On Use Of Business Incentive Tax Credits Cap period on the use of business incentive tax credits. Issuance of pre-funded warrants in connection with PIPE offering, net of offering costs Issuance of Pre funded Warrants in Connection With Private Investment in Public Equity Offering Net of Offering Costs Issuance of pre-funded warrants in connection with private investment in public equity offering net of offering costs. Investment In Available For Sale And Held To Maturity Securities [Line Items] Investment In Available For Sale And Held To Maturity Securities [Line Items] Investment in available for sale and held to maturity securities. Vehicles [Member] Vehicles [Member] Share based payment exercise price description Share-Based Compensation Arrangement by Share-Based Payment Award, Terms of Award Defined contribution plan, matching amount Defined Contribution Plan, Employer Discretionary Contribution Amount Weighted- Average Remaining Contractual Term, Options vested and exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Common Stock, Shares, Outstanding, Ending Balance Common Stock, Shares, Outstanding, Beginning Balance Common Stock, Shares, Outstanding Common Stock, Shares, Outstanding Risk-free interest rate Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Stock-based compensation Share-Based Payment Arrangement [Text Block] License And Collaboration Agreements [Abstract] License and collaboration agreements [Abstract] Financing Sources [Line Items] Financing Sources [Line Items] Financing Sources Line Items Supplemental disclosures of cash flow information: Supplemental Cash Flow Elements [Abstract] Expenses on milestone payments Expenses On Milestone Payments Expenses on milestone payments. Retirement Plan Type Retirement Plan Type [Axis] Tax Credit Carryforward Tax Credit Carryforward [Axis] Reconciliation of Unrecognized Tax Benefits, Excluding Amounts Pertaining to Examined Tax Returns [Roll Forward] Reconciliation of Unrecognized Tax Benefits, Excluding Amounts Pertaining to Examined Tax Returns [Roll Forward] Derivative Financial Instruments, Liabilities [Member] Derivative Financial Instruments, Liabilities [Member] Income Statement Location Income Statement Location [Domain] Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Weighted average exercise price per share Granted Summary of fair value of the financial instruments that are measured at fair value on a recurring basis Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block] Document Type Document Type Long term purchase commitment additional obligation to be paid Long Term Purchase Commitment Additional Obligation To Be Paid Long term purchase commitment additional obligation to be paid. Fair Value by Liability Class Fair Value by Liability Class [Domain] Net cash and cash equivalents provided by (used in) investing activities Net Cash Provided by (Used in) Investing Activities Share based payments weighted-average grant date fair value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested, Weighted Average Grant Date Fair Value Disposal Group Classification [Axis] Research and development credit carryforwards written off Deferred tax assets,tax credit carryforwards research written off Deferred tax assets,tax credit carryforwards research written off Net cash and cash equivalents provided by financing activities Net Cash Provided by (Used in) Financing Activities Entity Filer Category Entity Filer Category Deferred tax assets, research and development tax credit carryforwards Deferred Tax Assets, Tax Credit Carryforwards, Research Servicing Liability at Fair Value, Period Increase (Decrease), Total Change in fair value of liability Servicing Liability at Fair Value, Period Increase (Decrease) Supplemental disclosures of noncash financing and investing activities: Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Other than Temporary Impairment Losses, Investments, Total Other than temporary impairment losses, investments Other than Temporary Impairment Losses, Investments Increase (Decrease) in Accrued Liabilities, Total Accrued liabilities Increase (Decrease) in Accrued Liabilities Impairment of right of use assets Operating Lease, Impairment Loss Less: imputed interest Finance Lease Liabilities Undiscounted Excess Amount Finance lease liabilities undiscounted excess amount. Short-term Investments, Total Short-term investments Short-Term Investments Warrant Liability Warrant Liability [Member] Warrant Liability. APIC, Share-Based Payment Arrangement, Other, Increase for Cost Recognition Stock-based compensation expense related to employee stock awards Aggregate price for share repurchase. Aggregate price for share repurchase Aggregate price for share repurchase Asset Class Asset Class [Axis] Deferred Tax Assets, Tax Credit Carryforwards, Total Tax credits Deferred Tax Assets, Tax Credit Carryforwards Merck [Member] Merck. Merck PP&E Purchase still in Accounts Payable Capital Expenditures Incurred but Not yet Paid Total liabilities Liabilities Schedule Of Property Plant And Equipment [Table] Property, Plant and Equipment [Table] Purchases of short-term investments Payments to Acquire Short-Term Investments Emory university [Member] Emory University [Member] Emory university [Member] Total stockholders’ equity Beginning balance Ending balance Equity, Attributable to Parent Long term purchase commitment period description Longterm Purchase Commitment Period Description Long term purchase commitment period description. Proceeds from issuance of common stock in connection with PIPE offering, net of costs. Proceeds from issuance of common stock in connection with PIPE Offering, net of costs Proceeds From Issuance Of Common Stock In Connection With PIPE Offering Net Of Costs Documents Incorporated by Reference Documents Incorporated by Reference [Text Block] Net loss Net loss Net Income (Loss) State taxes, net of federal benefit Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent Finance Lease Finance Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract] Fair value measurements Fair Value Measurement, Policy [Policy Text Block] Statement of Financial Position [Abstract] Net operating losses written off Deferred tax assets operating loss carryforwards written off Deferred tax assets operating loss carryforwards written off. Weighted average shares of common stock, diluted Weighted average shares of common stock, diluted Weighted Average Number of Shares Outstanding, Diluted, Total Permanent differences Effective Income Tax Rate Reconciliation, Nondeductible Expense, Other, Percent Schedule of Expected Income Tax (Benefit) Computed Using Federal Statutory Income Tax Rate to Company's Effective Income Tax Rate Schedule of Effective Income Tax Rate Reconciliation [Table Text Block] Amortization of right of use assets Operating Lease, Right-of-Use Asset, Periodic Reduction 2023 Pre-Funded Warrants Two Thousand Twenty Three Pre Funded Warrants [Member] Two thousand twenty three pre funded warrants. Purchase price per share Shares Issued, Price Per Share Effective income tax rate Effective Income Tax Rate Reconciliation, Percent Vesting of early exercised common stock options Vesting Of Early Excercised Common Stock Options Value Vesting of early excercised common stock options, value. Federal Deferred Federal Income Tax Expense (Benefit) Summary of Pre-funded Warrant Shares Outstanding Summary of Pre-funded Warrant Shares Outstanding [Table Text Block] Summary of pre-funded warrant shares outstanding. Fixed-Maturity Securities, Amortized Cost, Total investments Available-for-sale securities, Amortized Cost Debt Securities, Available-for-Sale, Amortized Cost Government Assistance, Type [Axis] Weighted-average remaining lease term (years) Operating Lease, Weighted Average Remaining Lease Term Net periodic benefit cost Defined Benefit Plan, Net Periodic Benefit Cost (Credit) Defined Benefit Plan, Net Periodic Benefit Cost (Credit), Total Use of estimates Use of Estimates, Policy [Policy Text Block] Voting Power Axis Voting Power Voting Power [Axis] Income taxes Income Tax Disclosure [Text Block] Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items] Collaboration expire period Long-Term Purchase Commitment, Period Stock option exercise price Stock Option, Exercise Price, Increase Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Weighted average exercise price per share - Beginning balance Weighted Average Exercise Price Per Share - Ending balance Purchases of long-term investments Payments to Acquire Long-Term Investments Operating lease liabilities Deferred Tax Assets Operating Lease Liabilities Deferred tax assets operating lease liabilities. Total finance lease cost Finance Lease Cost Finance Lease Cost Schedule of Earnings Per Share, Basic and Diluted Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Leasehold improvements [Member] Leasehold Improvements [Member] Leasehold Improvements [Member] Income Tax Authority Income Tax Authority [Axis] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Fair Value Disclosures [Abstract] Total current provision for income taxes Current Income Tax Expense (Benefit) Fair Value Hierarchy and NAV Fair Value Hierarchy and NAV [Axis] More Than 10% [Member] More Than Ten Percent [Member] More Than 10% 2026 Finance Lease, Liability, to be Paid, Year Three Payments to Acquire Property, Plant, and Equipment, Total Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment Interest on lease liabilities Finance Lease, Interest Expense Operating lease option to extend Lessee Operating Lease Option To Extend Term Lessee Operating Lease Option To Extend Term. Number of awards, vested Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Share based payment awards granted Number of shares issued Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Granted Stock issued during the period new issues shares Issuance of common stock, shares Stock Issued During Period, Shares, New Issues Employee-related Liabilities, Current, Total Accrued compensation Employee-related Liabilities, Current Class of Warrant or Right [Axis] Income Tax Disclosure [Abstract] Tax Credit Carryforward, Name Tax Credit Carryforward, Name [Domain] Summary of Common Warrant Shares Outstanding Summary of Common Warrant Shares Outstanding [Table Text Block] Summary of common warrant shares outstanding. Impairment of long-lived assets Impairment or Disposal of Long-Lived Assets, Including Intangible Assets, Policy [Policy Text Block] Defined Benefit Plan, Funded (Unfunded) Status of Plan, Total Funded status Defined Benefit Plan, Funded (Unfunded) Status of Plan Net pension liability Increase (Decrease) related to current year positions Unrecognized Tax Benefits, Increase Decrease Resulting from Current Period Tax Positions Unrecognized tax benefits, Increase decrease resulting from current period tax positions